Dr DIMITRIOS – JAMES MANOS

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EUROPEAN PAEDIATRIC LIFE SUPPORT (EPLS) AT A GLANCE

NOTE
All the medical procedures and drug administration mentioned in this text should be done only under a senior doctor's consultancy. Some information in this text is empirical and its reliability can't be ascertained. It is suggested to search official medical articles, books and guidelines in order to ascertain the medical information & drug doses of this text.

1 DECEMBER 2009

 

NOTE

All the medical procedures and drug administration mentioned in this text should be done only under a senior doctor’s consultancy.

 

 

 

PAEDIATRIC BLS (BASIC LIFE SUPPORT) ALGORITHM

 

Safety first!

Stimulate. Don’t shake the kid, but with your one hand on its forehead and the other at its arm and shake its arm.

Assess for unresponsiveness.

Call loud its name and say ‘wake up’ or ‘are you Ok?’

No response: shout for help!

 

Open airway (head tilt & chin lift or jaw thrust, on trauma only jaw thrust)

Check for any foreign object and remove it with a single sweep.

 

Breathing assessment

Look, listen feel for 10sec.

 

a.      Breathing: place in recovery position.

b.     Not breathing

 

Place the baby supine at a neutral position (place a folded towel under the baby’s shoulders). However, place a child > 1 years old supine on a ‘sniffing position’ (with increased head extension than in neutral position)

Open the airway (jaw thrust or chin lift, use jaw thrust on trauma).

 

Give 5 rescue breaths (with a pocket mask or if available perform BMV, Bag Mask Ventilation with a self inflating Bag Mask with reservoir). On mouth to mouth rescue breaths don’t forget to close the victim’s nose.

On infants < 1 years old cover with your mouth the mouth and the nose of the baby, if you use mouth to mouth ventilations.  During each rescue breath check for visible chest expansion.

 

Check for pulse (10 sec) (carotid on children, brachial/ femoral on infants < 1 years old, umbilical on newborn)

 

A)    Pulse: Give 1 breath / 5 – 6 sec (10–12 breaths /min). Recheck pulse every 2min.

B)    No pulse or HR < 60: Start CPR compressions: rescue breaths ratio 15:2 (30:2 with a single non professional rescuer). On newborn the CPR ratio is 3:1.

 

Compressions 100/min in the middle of the chest. Ventilations 10/ min (1 every 5 sec). The duration of each ventilation is 1 – 1.5 sec. Ensure full chest recoil with the compressions. The depth of compressions is 1/3 of the chest’s diameter.

 

On infants (< 1 years old) perform compressions with your 2 fingers vertically on the child mid-chest. On newborn perform the 2 thumbs encircling technique. On small children, but older than infants (and younger than adolescents), perform compressions with your 1 hand.

 

Continue CPR for 1 min

 

Reassess

Check pulse

 No pulse: Activate EMT (Emergency Medical Team) – activate blue code & ask for defibrillator.

However if primary cardiac arrest (e.g. child with known cardiac disease) is suspected activate EMT and ask for a defibrillator before starting CPR.

Attach an AED (Automated External Defibrillator) on children > 1 years old. On children 1 – 8 years use pediatric attenuator, but if unavailable, use AED as it is.

ABCDs – PRIMARY SURVEY

 

·        Primary survey:

·        On A (airway) we check the airway’s patency. Open the airway. Is airway patent (e.g. the patient talks) or threatened (stridor or ‘snoring’) or obstructed?

 

o       A is also C Spine immobilization (on suspected injury). We open airway with jaw thrust or chin lift (we use jaw thrust on suspected C – spine injury), we do suction (e.g. of vomits), we place an oropharengeal airway (if the airway’s patency is threatened and also if no gag reflex) or nasopharyngeal airway (contraindicated in apnoea, nasal injury, cribiform fracture and basal skull fracture) and we consider soon a permanent airway (e.g. ET endotracheal intubation).

 

o       On A we also check tracheal position and also in older children for JVD (jugular vein distension).

·        Traps on A (airway) are cribiform and face trauma and also base skull fracture with ear or nose leakage of CSF, racoon eyes, blood from the ear and Battle sign with haematoma behind the ears (in the above cases the nasal airway or the nasogastric tube are contraindicated because they may enter to the brain!).

·        On B (breathing) we check RR (respiratory rate), chest expansion (if it is equal bilaterally, otherwise suspect e.g. flail chest on trauma), we ausculate the chest (is breathe sound bilaterally equal? Any wheezing?), we percuss the chest (any tympany?) and take oxygen saturation (SpO2).

 

o       Also we check for central cyanosis (tongue & lips, central cyanosis is always combined with peripheral) or peripheral cyanosis (finger nails – exclude hypothermia). SpO2 is unreliable on methemoglobinemia (may be manifested with asymptomatic cyanosis, it may be caused from drugs) and CO (carbon monoxide) poisoning.

 

o       What is the respiratory effort and depth? Is breathing shallow and laboured? Is oxygen saturation low? Does the child has sub and intercostals recession, xiphoid retraction, nasal flaring, use of assessor muscles (e.g. sternoclidomastoids), head bobbing up and down with each respiration, see – saw (rocking) respiration (movement of the abdomen during inspiration) and grunting (babies)? All the above indicate respiratory distress. 

 

o       Also always give oxygen:

o       On patients WITHOUT significant hypoxia (SpO2 Oxygen saturation) and WITH ADEQUATE breathing we give oxygen with nasal cannula 2 – 4 L/min.

 

o       On patients WITH significant hypoxia but ADEQUATE breathing we give O2 (oxygen) with a non rebreathing face mask with reservoir bag and flow 15 L/min.

 

o       In case of INADEQUATE breathing or APNEA we perform BMV bag mask ventilation with a self inflating bag with reservoir and oxygen supply and flow 15 L/min.

 

o       We keep always SpO2 oxygen saturation > 90%.

 

o       Patients with significantly increased or decreased RR respiratory rate need BMV bag mask ventilation.

 

o       Also on patients with GCS <_ 8 we intubate (we use RSI rapid sequence intubation if GCS is >3).

 

·        Traps on B (breathing) are vulnerable ages (on children rib fractures are rare; if they occur they indicate severe lung injury such as lung contusion). 

·        On C (circulation) we check pulse (radial and carotid on children, brachial and femoral on babies). Is it fast and thready? Is it regular or irregular? BP and pulse pressure (SBP systolic BP – DBP Diastolic BP). BP will fall with > 40% volume loss.

 

o       We obtain vascular (IV/IO) access (2 wide IV lines on trauma). On hypovolemia (from trauma or dehydration) we give NS (normal saline) or RL (Ringers - Lactated), reassess and also consider early to transfuse blood (if not type available give Group O Rh negative). On trauma fluids should be warm (39 degrees C)! On hypovolaemic children we give 20 ml/kg fluids bolus over 5 – 20min. If no response, we repeat 20 ml/kg and if shock still remains we give 15 ml/kg packed red blood cells PRC to 10 ml/kg crystalloids or we give 10 ml/kg whole warmed blood. On  hypovolaemic newborns we give10 ml/kg fluids over 5 – 10 min (in arrest).

 

o       After IV access we also take blood for Labs (including pregnancy test on child bearing age women, toxicology, coagulation and blood type and crossmatch – we ask blood units for transfusion).

 

o       Signs of shock:

o       On children, on < 25% of circulating blood volume loss, there is mildly increased HR heart rate, moderate increased RR respiratory rate, normal or increased (!) peripheral pulse volume, normal or increased capillary refill time, cool/pale skin and mild agitation. Οn shock, systolic BP will fall if more than 40% of circulation blood volume is reduced on children!

 

o       Ο C we also look the color and temperature of the skin (a cold clammy mottled or pale or with cyanosis skin may indicate shock, however exclude low ambient temperature!), the peripheral pulses, the capillary refill time (normal is when < 2 sec, on 5 sec finger nail pressure or on the babies on sternum pressure), the LOC (level of consciousness) and also for babies the interaction with the parents or the presence of uncontrolled cry. 

 

o       We also check the preload with JVD (jugular vein distension). In case of JVD, we need to exclude heart failure, pulmonary embolism (rare), cardiac tamponade and tension pneumothorax). We also check for leg and pulmonary oedema (both are rare on children) and liver distension (that is more significant sign on children!). 

 

o       We also connect to a monitor, and – if indicated (e.g. arrhythmia or heart contusion on trauma) we take a 12 lead ECG. If there is time, we may also take ABGs (arterial blood gases) to check e.g. for acidosis.

·        On D (disability) we check AVPU (Alert, responds to Voice, responds to Pain, Unresponsive), or if there is time (and always on trauma) we check GCS (Glasgow comma scale). We also check pupil’s size & reaction to light and also for abnormal postures of flexion (decorticate) or extension (decerebrate). On GCS <_ 8 intubate (use paralytics – anaesthetics if GCS > 3). On AVPU, response only to pain indicates GCS about 8. Check then the GCS.

·        Traps on D (disability) are: lucid interval on epidural hematoma, brain’s vasoconstriction from hyperventilation and also increasing ICP during intubation (prevent it with lidocaine and etomidate – the last is contraindicated on hypotension – in that cases stabilize first the patient with fluids).

·        Οn E (Expose, Environment) we expose the patient (from his/her clothes) and check the skin for clues (wounds, rash, belt sign on car accident etc). We also perform log roll and check the back. Next we prevent hypothermia e.g. with blankets. E is also to call Expert!

·        Traps on E are hypothermia which complicates clotting.

·        We also check the kid’s temperature! 

·        Aids on ABCDs are ABGs (arterial blood gases), SpO2 (oxygen saturation), CO2 detector (capnographer or oesophagal detector) after intubation), Foley, Levine (nasogastric tube), ECG and FAST/ ultrasound.  DPL (diagnostic peritoneal lavage) is unreliable on children.

·        Secondary survey οn trauma is the examination from head to toes. We check pulses and also check for lacerations, edema, deformity, paleness, tenderness, crepitation, surgical (subcutaneous) emphysema, joints mobility, sensory examination, reflexes and neurological examination etc. We use X’ Rays, Doppler, CT etc.

·        The emergency needs to be transferred to the nearest APROPRIATE (trauma) medical centre/ hospital.

·        TRIAGE is based to factors such as ABCs, the available means (personnel and devices), if we have a mass destruction, the number of victims, the time and distance for definite care, the severity of the injury and the bigger chance for survival (in case of a patient with a very serious injury that is not compatible with life, or in a case of no pulse, we go on with the rest patients and ‘flag’ this patient with black color – or blue in some countries, i.e. expectable to die). Triage is continuing (dynamic).

·        On trauma we do not forget log roll.

·        On secondary survey always we ask AMPLE (Allergy, Medication, Past medical history, Last meal and Environment/Events). Some prefer to ask it from the very first.

 

 

 

PULSELESS ARREST, ALS (Advanced life support) ALGORITHM

 

For initial steps see above ‘BLS’ algorithm.

 

Attach monitor/ defibrillator.

Attach an AED (Automated External Defibrillator) on children > 1 years old. On children 1 – 8 years use pediatric attenuator, but if anavailable, use AED as it is.

 

a.      Shockable rhythm (VF ventricular fibrillation, pulseless VT ventricular tachycardia).

 

 

 Gel

(Put gel on chest)

 

Joules:

1st shock: 4 J/Kg (ACLS: 2 J/Kg for 1st shock).

 

Paddles (1st paddle below the right clavicle, 2nd on the left axilla at the left mid-axillary line)

 

In case of a patient with a pacemaker or an ICD (implantable cardiac defibrillator), place the defibrillator’s pads or paddles at least 12 – 15 cm away from the pacemaker or the ICD to avoid burning the myocardium! 

 

[Before each shock remove oxygen supply (nasal cannulae or oxygen mask or self inflating bag) 1 meter away or close the ventilator! Ensure no one touches the patient (say: ‘I am going to shock on three. One, I am clear. Two, you are clear. Three, everyone is clear’.]

 

 

1st Shock

  Resume immediately CPR for 5 cycles of 15:2 (2 min)

 

Reassess rhythm & pulse

 

Shockable rhythm

 

2nd shock 4 J/Kg

 

 

Immediately resume CPR for 2 min

Give epinephrine (adrenaline) 10 mcg/ kg rapid IV/IO push.

 

Epinephrine (adrenaline) dose is 10 mcg/kg IV/ IO namely 0.1 ml/kg of 1: 10.000 solution (1 mg/ 10 ml). If you use ET (endotracheal) rout, although the dose administration is unpredictable, give 100 mcg/kg (0.1 ml/kg) of 1: 1000 solution (1mg/ 1ml).

 

 

Check monitor/ rhythm

 

Shockable rhythm

 

3rd shock 4 J/Kg

 

Immediately resume CPR for 2 min

Give amiodarone 5 mg/kg IV/IO (diluted in D5W 5% dextrose) rapid IV push. 

 

Amiodarone may be repeated at max dose up to 15 mg/kg/day.

4th shock

 

etc.

ΝΟΤΕS:

 

·        Give epinephrine every 3 – 5 min (after alternating shocks or every 2nd loop).

 

·        Rotate compressors every 2 min.

 

·         For arrest from VT with hypomagnesaemia or on Torsades de points give MgSO4 magnesium sulphate 25 – 50 mg/kg IV/IO (diluted in D5W 5% dextrose), over 10 – 20 min (max 2 gr).

·        On ACLS alternative to amiodarone is lidocaine 1,5 – 2  mg/kg IV/IO (it may also given via ET). 

·        After intubation, compressions and ventilation are performed asynchronized. This is not the case on newborn ALS.

·        On infants, if infant paddles are unavailable you may use anterior – posterior placement of the paddles.

·        When the defibrillator/ AED is analyzing the rhythm and also during the defibrillation ensure no one touches the patient.

 

b.     Non shockable rhythm (asystole or PEA Pulseless Electrical Activity)

 

In case of asystole

1.      Check another lead.

2.      Check if electrodes are detached.

3.      Increase Gain and sensitivity of the monitor.

 

 

  On asystole or PEA:

 

·        Resume CPR.

·        Perform ET (endotracheal) intubation and establish IV/IO access. IO access is the rout of choice on PEA or asystole!

·        First give epinephrine 10 mcg/ kg (0.1 ml/kg of 1 : 10.000 solution) rapid IV/IO push. Repeat every 3 – 5 min (every 2nd loop).

·        Also give atropine 20 mcg/kg (0.02mg/kg) (min 100mcg i.e. 0.1 mg) on asystole with P waves or suspected vagotony (from increased vagal tone) or PEA with HR < 60. Repeat atropine every 3 – 5min (every 3 min on asystole) to max of 3mg (ACLS: max dose 1mg on children and 2 mg on adolescents).

·        Consider TCP (Tran – Cutaneous Pacing) if bradycardia is caused by complete heart block or Mobitz (II) 2nd degree AV block or sick sinus syndrome or on a transplanted heart.

·        On PEA, in case of suspected hypovolaemia, give 20 ml/kg (10 ml/kg over 5 – 10 min for newborn) bolus normal saline. 

·        Check also reversible causes (6 Hs and 6Ts).

 

 

 TERMINATION OF ALS

Consider termination of ALS (advanced life support) if acceptable BLS (basic life support) was provided, advanced airway was placed and successfully maintained, shockable rhythms were defibrillated, IV/IO access was established, al the appropriate drugs were administered, potentially reversible causes were ruled out or corrected and the family has been updated on the probable negative outcome of continued ALS.

 

 

 

 NOTES ON ARREST:

 

·        Administration of medications (such as adrenaline) on peripheral lines on emergencies should be followed immediately by flush with normal saline (2 – 5 ml on children) and elevation of the extremity for 10 – 20 sec to facilitate drug delivery to the central circulation.

·        In case we use the ET (endotracheal) rout for drug administration we give higher doses than the IV dose and flush the drug with 1 – 2 ml NS (normal saline) and ventilate. The ET rout gives unpredictable dose of drug. It is not recommended on newborn. Also glucose is contraindicated via ET rout.

·        Many of the drugs referred below, as well as fluids, can be administrated via IO (intra - osseous) rout, especially on children.

·        IO rout is the rout of choice on children with PEA (pulseless electrical activity), asystole and also if 3 attempts of IV access have failed or take more than 90 sec. 

·        Endotracheal doses (e.g. epinephrine, lidocaine, atropine, naloxone, amiodarone) is 2 – 2.5 times the recommended IV/IO dose.  Glucose (dextrose) is NEVER given endotrachel route. Also DON’T give glucose with blood.

·        Dextrose dose on hypoglycemia is 5 – 10 ml/kg of 10% dextrose. On neonates the dose is 2.5 ml/kg. Never give it via ET (endotracheal tube) and don’t mix it with blood. On newborn dextrose may be useful on arrest.

·        Naloxone dose is 100 mcg /kg (0.1 mg/kg) IV/IO/IM for kids < 5 years old and 2 mg for children > 5 years old. Avoid it on a newborn of a chronic opioid abuse mother because it may manifest withdrawal syndrome (in this case call expert).

·        Bicarbonate dose on arrest is 1mEq/kg (1 mMole/ kg) of 8.4 % solution IV/IO. On newborn use 4.2% solution. Don’t mix them in the same line with epinephrine (adrenaline) or other sympathiticomimetics such as dopamine. At least clean with saline the line.

 

 

REVERSIBLE CAUSES OF ARREST TO RULE OUT OR CORRECT

 

Reversible causes to be excluded and corrected in arrest are the 6 Hs & 6 Ts.

 

The 6 Hs include Hypovolemia, Hypoxia, Hydrogen ion (acidosis), Hypo/hyperkalemia, Hypoglycemia and Hypothermia.

 

The 6 Ts include Toxins/Tablets (poisoning), Tamponade cardiac, Tension pneumothorax, Thrombosis coronary, thrombosis pulmonary and Trauma. 

 

·        Hypovolaemia causes narrow QRS tachyarrhythmia.

·        Hypoxia causes narrow QRS bradyarrhythmia.

·        Acidosis usually causes bradyarrhythmia or other arrhythmias.

·        Hyperkalemia causes very tall (tended) peaked T waves (T waves larger than R waves in > 1 lead !), 1st degree AV (atrioventricular) block, sinus bradycardia, AV blocks, flattened or absent P waves, ST depression (!), S & T waves merging, wide QRS, VT, arrest (pulseless VT, VF, asystole, PEA).

·        Hypokalemia causes QT prolongation (such as hypomagnesaemia), flat T wave, 1st degree AV block, U waves (!), ST elevation (!), variable arrhythmias, VT, arrest (pulseless VT, VF, asystole, PEA).

·        Hypoglycemia causes tachycardia (may not appear if on β’ blockers). It also may cause ST depression or AV block. It also (as well as liver failure) may cause hemiplegia and other focal neurological signs and seizures.  

·        Cardiac tamponade causes narrow QRS tachyarrhythmia or PEA.

·        Tension pneumothorax causes narrow complex tachyarrhythmia or bradyarrhythmia (because of the hypoxia) or may cause PEA.

·        Οn hypovolemia give 20 ml/kg normal saline bolus (on newborn give 10 ml/kg over 5 – 10 min) and reassess.

·        Except trauma, suspect hypovolemia from dehydration (e.g. high fever and/or severe/ prolonged diarrhea and/or vomiting).

·        On hypoxia and acidosis ensure effective oxygenation and ventilation. Then consider on acidosis sodium bicarbonate.

·        Consider bicarbonate on metabolic acidosis (confirmed by ABGs arterial blood gases), TCA (Tricyclic antidepressants) OD (overdose) and also on prolonged (> 10 min) arrest. However, its potentially harmful on patients with hypercarbic acidosis.

·        Suspect electrolyte abnormalities on history (renal failure, recent dialysis, diuretics, severe diarrhea or vomiting etc).

·        On hypothermia do only 1 defibrillation and withhold drugs until core body temperature is > 30 degrees C (86 degrees F).

·        On poisoning/ overdose consider decontamination, gastric lavage, active charcoal, whole bowel irrigation, dialysis, antidotes.

·        Tension pneumothorax is characterized by JVD (jugular vein distension – if not hypovolemic), absent breath sounds and hyper- resonance on the affected side, decreased compliance on ventilating. Late sign is contralateral tracheal shift.

·        Massive pulmonary embolism is characterized by sudden onset of  dyspnea, pleuritic (on inspiration) chest pain, cyanosis, and JVD. It may cause PEA.

·        Tension pneumothorax, cardiac tamponade and pulmonary thrombosis are obstructive causes of PEA.

 

 

ITD DEVICE

 

ITD device is Impendence Threshold Device. It attaches to the self inflating bag mask or the tracheal tube. It let the patient to exhale if spontaneous breathing returns. It also does not permit the equalization of negative intra-thoracic pressure in case of hyperventilation. When we use it with BMV (bag mask ventilation), two rescues need to perform ventilation. When we open the ITD it has lights that open 10 times/min. During each light we ventilate.

 

AIRWAY OBSTRUCTION BY A FOREIGN BODY ACLS ALGORITHM

 

·        On a child that chokes from a foreign body:

 

a.      If the child is conscious and the cough is effective, we encourage it to cough.

 

b.     In case of a choking child > 1 years old that is conscious but cough isn’t effective (the child can’t talk, or has stridor, or cyanosis) we give with our palm (thenar) 5 back blows between its scapulae & 5 abdominal thrusts (Heimlich maneuver). We give chest thrusts (instead of abdominal) on pregnant or obese patients, instead of abdominal thrusts.

 

 

We reassess. We repeat the maneuvers until the foreign object is expelled (we inspect the mouth and remove any visible object with a single sweep) or the child becomes unconscious.

 

If the child becomes unconscious, we call for help (activate the blue code/ EMT) and go to the unconscious algorithm.

 

 

c.      In case of a choking infant < 1 years old that is conscious but cough is ineffective (the baby doesn’t make sounds, does not breathe effectively or doesn’t cry; or is cyanotic) we call for help.

 

The infant may be positioned supine – lying inverted on our arm – and in that position we give 5 chest thrusts and then turn it opposite – prone (with a ‘sandwich’ maneuver) – and give 5 back blows). We support the infant’s head during the maneuvers by cupping its face with our hand (without obstructing its airway). We continue the maneuvers until the foreign object is expelled (we inspect the mouth and remove any visible object with a single sweep) or the child becomes unconscious.

 

d.     If the child (in any age) becomes unconscious: we place the child supine, (neutral position on infants < 1 years old – we place a folded towel under the child’s shoulders to keep this position, or use a ‘sniffing position’ for older children – with a little bit increased extension than the neutral position) open the airway and give 5 rescue breaths. If no effective ventilations, we reposition the kid’s head and attempt to ventilate again!

 

If still no effective ventilation, we start chest compressions and go on with CPR for 1 min and reassess. We inspect the mouth and remove any visible object with a single sweep.

 

If still absent or not effective ventilations, we call EMT (Emergency medical team)/ blue code.

 

The foreign object may be removed under direct laryngoscopy with a Magill’s forceps, if available. Other option is needle cricothyrotomy.

 

In case the patient resumes breathing, we place in recovery position.

 

 

WHAT TO CHECK ON MONITOR/ ECG

1.      Is there electrical activity and recognizable QRS?

2.      Which is the ventricular rhythm? It is 300/ large squares between RR waves.

3.      Are the QRS regular? If not, exclude e.g. ectasystoles.

4.      Which is the QRS width? If > 0.08 sec (2 small squares) it is wide. Then exclude ventricular arrhythmia or BBB (bandle branch block).

5.      Is there atrial activity? Check for P waves on II and V1 leads.

6.      Which is the relationship between atrial and ventricular activity? Is it 1:1 each P followed by QRS) as normal, or is it variable or there is no relationship?

 

 

TACHYARRHYTMIA ALGORITHM ON CHILDREN

·        We give supplemental oxygen.

·        We connect to monitor (we put it to II lead).

·        We place IV/IO access, take blood for Labs and keep it open with normal saline.

·        We have suction and intubation equipment available

·        We take a 12 lead ECG

 

We open the monitor on II lead.

 

Tachycardia is defined as HR > 160 bpm for children > 1 years old and > 180 bpm for children < 1  years old.

 

Is the patient is unstable? AN UNSTABLE tachycardia is characterized by one or more of the following: decreased LOC (level of consciousness), hypotension, chest pain, heart failure (e.g. liver enlargement), dyspnea etc.

 

A.     Narrow complex tachycardia (QRS <_ 0.08 sec or <_ 2 small squares).

 

Diagnostic possibilities:

 

1.      Probably Sinus tachycardia if compatible history, gradual onset, ECG: present & normal P waves, beat to beat R- R variability, HR varies with activity, normal PR and also HR < 220 bpm for infants (< 1 years old) and < 180 bpm for children > 1 years old. History clues for sinus tachycardia are fever, hypovolaemia (hemorrhage, dehydration), anemia, fear/ stress, pain and respiratory failure. On sinus tachycardia treat the cause!

2.      Probably SVT (Supra – Ventricular Tachycardia). SVT is characterized by abrupt onset, non specific & non clear etiology, P wave absent or abnormal, no beat to beat R –R variability, and HR > 220 bpm for infants (< 1 years old) and > 180 bpm for children > 1 years old.

 

 

Treatment of narrow complex tachycardia:

 

a.      Stable patient:

 

Initially we perform vagal maneuvers such as unilateral carotid sinus massage or to blow the plunger of a syringe or place an ice bag transiently over the face (place it not immediately on the face, but on a towel).

 

If unsuccessful we give adenosine 0.1 mg/kg rapid IVP (IV push) or IO  (over 1 – 3 sec) to max dose of 6 mg.

 

If unsuccessful, we repeat after 1 – 2 min at 0.2 mg/kg to a max dose of 12 mg.

 

Each dose should be followed by 3 – 5 ml saline flush and arm elevation for 10 – 20 sec. The injection should be performed on a close to heart vein (e.g. antecubital fossa).

 

If still unsuccessful, we call expert.

 Don’t give verapamil on SVTs because it may cause hypotension.

 

 

b.     Unstable patient:

 

We perform SYNCRONIZED cardioversion (under sedation if patient isn’t unconscious).

 

Gel, Joules (push synchronized button), paddles & oxygen removal.

 

1st shock is 1 J/Kg. If unsuccessful, we repeat with 2 J/kg. We give amiodarone 5 mg/kg IV/IO (diluted in D5W 5% dextrose), over 20 – 60 min.  Max dose of amiodarone is 15 mg/kg/day. We may repeat with 3rd shock.

 

 

B.    Wide complex tachycardia (QRS > 0.08 sec or > 2 small squares).

Possible VT (ventricular tachycardia).

 

a.      Stable patient:

 

We give adenosine 0.1 mg/kg rapid IVP (IV push) or IO (over 1 – 3 sec) to max dose of 6 mg.

 

If unsuccessful, we repeat after 1 – 2 min at 0.2 mg/kg to max dose of 12 mg.

 

Each dose should be followed by 3 – 5 ml saline flush and arm elevation for 10 – 20 sec. The injection should be performed on a close to heart vein (e.g. antecubital fossa).

 

If unsuccessful, we call expert.

 

We give amiodarone 5 mg/kg IV/IO over 20 – 60 min. Max dose of amiodarone is 15 mg/kg/day.

 

 

 

 

b.     Unstable patient:

 

We perform SYNCRONIZED cardioversion (under sedation if patient isn’t unconscious).

 

Gel, Joules (push synchronized button), paddles & oxygen removal.

 

1st shock is 1 J/Kg. If unsuccessful, we repeat with 2 J/kg. We give amiodarone 5 mg/kg IV/IO over 20 – 60 min. Max dose of amiodarone is 15 mg/kg/day.

 

We may repeat with 3rd shock

 

 

NOTE

Alternative to amiodarone on ACLS tachyarrhytmia algorithm is procainamide 15 mg/kg IV over 30 – 60 min.

 

 

BRADYCARDIA

Bradycardia is defined as HR < 60 bpm for children > 1 years old and < 80 bpm for infants (< 1 years old).

 

Is the patient is unstable?

 

Adverse signs on bradycardia are hypotension, HR < 40 bpm, heart failure (e.g. liver enlargement), ventricular arrhythmias compromising BP, shock and respiratory distress.

 

Risk factors for asystole are recent asystole, type II (Mobitz II) 2nd degree AV (atrioventricular) block, complete heart block with broad QRS and ventricular pauses > 3 sec. In the above factors perform TCP (Transcutaneous Pacing) a.s.a.p (as soon as possible). TCP is also indicated on denervated (e.g. transplanted) heart where drugs will not work.

 

Relative bradycardia is the phenomenon where HR is faster than the one that would expected for the patient’s condition. For example a patient 17 years old with HR 65 bpm and BP 80/ 50 has relative bradycardia because HR is too slow, relative to (regarding to) the BP.

 

 

 

 

BRADYCARDIA ALGORITHM

 

·        We give supplemental oxygen.

·        We connect to monitor (we put it to II lead).

·        We place IV/IO access, take blood for Labs and keep it open with normal saline.

·        We have suction and intubation equipment available

·        We take a 12 lead ECG

 

We open the monitor on II lead.

 

Paediatric bradycardia is usually result of hypoxia!

 

Check if there are there any adverse signs (see above)?

a.      If no, we support ABCs and call expert.

b.     If yes, we oxygenate, ventilate and intubate. We start CPR if HR< 60 in an infant or child, in spite of good oxygenation and ventilation. So if HR < 60 and there are signs of impaired or absent circulation we start CPR and:

 

·        We give epinephrine 10 mcg/ kg (0.1 ml/kg of 1 : 10.000 solution) rapid IV/IO push. We repeat every 3 – 5 min (every 2nd loop).

·        Also we give atropine 20 mcg/kg (0.02 mg/kg) (min 100mcg i.e. 0.1mg) on asystole with P waves or suspected bradycardia from increased vagal tone (e.g. from prolonged suctioning or ET endotracheal intubation). We may repeat atropine every 3 – 5min (every 3 min on asystole) to max of 3mg (ACLS: max dose 1mg on children and 2 mg on adolescents).

·        Consider TCP (Tran – Cutaneous Pacing) if bradycardia is caused by complete heart block or Mobitz II 2nd degree AV block or sick sinus syndrome or on a transplanted heart.

 

 

 

NEWBORN LIFE SUPPORT ALGORITHM

 

Birth

Breathing or crying?

Good muscle tone?

Term gestation? Preterm (premature) is a newborn of < 37 weeks.

Amniotic fluid clear? If not, is meconium thick?

 

a.      Yes: Provide routine care, warmth, dry and clear airway if needed.

 

b.     Νο

 

1.      Provide warmth. Use warm towels. After delivery remove the wet towel and cover the baby’s head and body with a new warm towel, (don’t cover the face!).

2.      Position the airway.

3.      Dry, stimulate (by rubbing the baby’s back or flicking its soles) & reposition the airway.

4.      Clear the airway if needed. Suction should be applied max for 5 sec. The suction tube length on newborn is 12 – 14 Fr and negative pressure max 100 mmHg. 

On a newborn, firsts we perform suction of the mouth and next suction of the nose. 

 

 

Assess breathing, HR (umbilical artery/ ausculate the chest with a neonatal stethoscope) and color.

 

Apnoeic or HR < 100 bpm: Call for help!  

 

 

Give positive pressure ventilations for 30sec

 

On newborn arrest for the first few breaths the inflation pressure is kept 30 cmH2O (20 – 25 cm H2O for preterms) and each rescue breath is applied 5 times, for 2 – 3sec each.

 

 Reassess pulse

HR < 60 bpm

Ensure effective lung ventilation.

Then add chest compressions. Continue CPR for 30 sec.

 

Reassess pulse

HR< 60 bpm

 

1.      Further chest compressions. CPR rate on newborn is 3: 1.

 

The compressions on newborn are 120/min and the ventilations on newborn are 30/min. On newborn arrest, compressions & rescue breaths are perform synchronized (and not simultaneously), with 3:1 rhythm.

 

2.      Obtain IV access (umbilical vein) or IO.

3.      Consider adrenaline.

Epinephrine (adrenaline) dose is 10 mcg/kg IV/ IO namely 0.1 ml/kg of 1: 10.000 solution (1 mg/ 10 ml). ET (endotracheal) rout for drug administration is not recommended on the newborn.

 

4.      Consider fluid administration. Fluids dose on newborn are 10 ml/kg IV/IO over 5 – 10min.

 

5.      Consider sodium bicarbonate (for acidosis e.g. for prolonged arrest – take ABGs) 1 – 2 mEq/kg of 4.2% solution (1 – 2 mmole/ Kg) IV/IO over 2 min. Don’t give it at the same IV line with catecholamines (e.g. adrenaline or dopamine). At least flush first the line with normal saline. Also after the bicarbonate administration ensure good ventilation. Avoid it on hypercarbic acidosis.

 

6.      Also consider glucose if no response to adrenaline and bicarbonates.  However in case of bolus of hypertonic solutions there is a risk for intra-ventricular hemorrhage on premature newborn. Don’t give glucose via ET rout and also don’t mix it with blood. The dextrose dose on newborn is 2.5 ml/kg

 

 

 

NOTES

·        On newborn needs intubation if insufficient bag mask ventilation, or if prolonged ventilation is needed, or if there is meconium and the baby is cardio-respiratory compromised or in case of congenital diaphragmatic hernia.

·        In case of thick meconium, we perform suction on a newborn with HR< 100, absent or insufficient breaths and not vigorous – with poor muscular tone. We do suction of the hypo-pharynx under direct vision. Then we intubate, we perform suction again – we aspirate the meconium under the vocal cords and next we do orogastric suctioning. Next, we remove the suction tube with the ET (endotracheal) tube (together; the meconium is stuck on the ET tube!) continuing suction of the oropharynx. If after the extubation HR is < 100 and > 60 we perform again intubation and suction. If HR is < 60 we perform the newborn arrest algorithm.

·        During CPR, keep the newborn on neutral position (with a folded towel below its shoulders. That’s because the baby’s head is larger than older children’s in which we prefer the sniffing position with a more increased head extension than the neutral position ). The airway may be kept open with an oropharengeal tube, until intubation is performed.

·        To prevent hypothermia on a very preterm baby, wrap it e.g. with a plastic food grade wrapper, without drying it first with a towel. Next, place it under a special radiant warmer.

 

 

NEVER FORGET:

·        Safety first.

·        Push ‘sync’ synchronized button on cardioversion.

·        Remove oxygen 1 meter away or close the ventilator before the defibrillation or cardioversion.

·        Take finger stick glucose on seizures.

·        Don’t forget IV/IO access on C – circulation (take blood for labs, keep it open with normal saline).

·        Rule out and treat 6Hs & 6Ts reversible causes of arrest (especially in asystole or PEA).

·        On an unconscious patient follow the intra hospital CPR/ AED algorithm. Before checking for breathing, open the airway (chin lift or jaw thrust, jaw thrust only on trauma).

·        Do not interrupt the chest compressions (a very common mistake) for any reason. However, if needed (e.g. for intubation) interrupt it just for a few seconds. There are special devices that perform automatically chest compressions. 

 

 

 

 

APPENDIX (I): COMMON CAUSES OF SHOCK

 

 What to rule out on a shock:

a) Traumatic blood loss. Check for bleeding in chest. Perform CXR, FAST. Check for pelvic or long bone fracture. If so, do immobilization.

b) Non traumatic volume loss. Exclude dehydration (diarrhea or vomiting). Also exclude GI bleeding (e.g. Meckel’s diverticulum). Perform USS (ultrasound). Call expert.

c) Dysrhythmia or cardiac failure (liver distension on children) Perform an ECG and CXR (chest X’ Ray). Call expert.

d) Tension pneumothorax on trauma or after positive pressure ventilation or spontaneous (bulla rupture). Are there any decreased unilateral breath sounds, tracheal deviation (away from the pneumothorax), hyper-resonant hemithorax on percussion or distended neck veins (if not hypotensive with blood loss)? Don’t wait for CXR! Perform needle decompression and next insert a chest tube.

e) Cardiac Tamponade (on trauma or pericarditis).Are there distended JVD (jugular veins distension), muffled heart sounds, low ECG voltage and electrical alterance, or pulsus paradoxus? Perform FAST/ USS (ultrasound). 

f) Anaphylaxis. Any history? Is there angioedema, laryngeal edema with stridor, wheezing, hives on skin?

g) Spinal Cord Injury – Neurogenic shock with decreased HR. Check for a motor/ sensory level of paralysis and anesthesia. Take cervical spine protections. Check rectal tone and check for blood.

h) Warm skin? If so, consider sepsis, neurogenic shock, anaphylactic shock, medication poisoning (e.g.β’ or Ca blockers).

i) Poisons/ medication overdose or SEs (Side Effects). Also illicit drug abuse, glue sniffing, mushrooms poisoning.

j) Sepsis and Adrenal Insufficiency.

• PH of venous blood is usually 0,01 – 0,03 lower than the arterial blood PH. Also PCO2 is 6 mmHg higher and bicarbonate is 2 meq/L higher by using venous blood.

• Anion gap is ([Na] + [K]) – ([Cl] + [HCO3]) and normal values are 12 – 16 mEq/L (usually 10 -1 2mEq/L).  Increased anion gap occurs on DM (diabetes melitus), alcoholics, starvation, lactic acidosis, renal failure, exogenous toxins metabolized to lactate (cyanide – CN, CO, ibuprofen, strychnine, toluene, iron – Fe and INH - isoniazide), or exogenous toxins metabolized to acids (aspirin, methanol, ethanol, ethylene glucol, paraaldeyde and rarely with isopropanol), severe hypotension, seizures and hypoxemia.

• Increased osmolar gap may occur in DKA, ethylene glycole or methanol or ethanol or isopropanol poisoning. Osmolar gap ΔOsm = measured Osm – Calculated O.

 

 

APPENDIX (II): GCS (GLASGOW COMMA SCALE)

 

Eye Opening (E4)

4  0 – 1 years old: spontaneously; > 1 years old: spontaneously

3  0 – 1 years old: to shout; > 1 years old:  to verbal command (not 

 necessarily to ‘open your eyes’)

2  all ages: to pain

1  all ages: no response  

Response to pain is checked by pressing the patient’s nail’s bed with a pen. If not response, try supraorbital pressure and sternal pressure. 

 

Best Verbal Response (V5)

5  0 – 2 years old: appropriate cry, smiles;  2 – 5 years old: appropriate words and phrases; > 5 years old: oriented, converses

4  0 – 2 years old: cries; 2 – 5years old: inappropriate words; > 5 years old:  confused

3  0 – 2 years old: inappropriate cry; 2 – 5 years old: cries, screams; > 5 years old:  inappropriate words

2  0 – 2 years old: grunts; 2 – 5 years old: grunts, sounds; > 5 years old:  incomprehensible e.g. moans

1  all ages: no response

 

Best Motor Response (M6)

6  0 – 1 years old: moves spontaneously and adequately; > 1 years old:  obeys command

5  all ages: localizes pain  

4  all ages: flexion withdrawal

3  all ages: decorticate (stereotypical flexion)

2  all ages: decerebrate (stereotypical extension) 

1  all ages: no response 

 

Motor response may be e.g. ‘raise your hand’. It is the better response of any limb. Decorticate posture is characterized by flexion of upper extremities. Decerebrate posture is characterized by internal rotation of shoulder & arm pronation and limb extension.

 

 

Score: min 3, max 15. If GCS<_8 the patient needs intubation (RSI rapid sequence intubation if GCS > 3). GCS <_8 severe injury, GCS 9 –12 moderate injury, GCS 13–15 minor injury. 

 

 

APPENDIX (III): Normal vitals:

 

a)   RR (respiratory rate)

Neonates (until 6th week) min 30/min and max 50/min.

Infants until preschool age min 20/min and max 30/min.

Teenagers min 12/min and max 20/min.

  

b)  HR (heart rate)

 Neonates min 100bpm and max 150 bpm.

 Infants min 80 bpm and max 120 bpm.

 Preschool age until school age min 60 bpm and max 110  

 bpm.

 Teenagers/adults min 60 bpm and max 100 bpm.

 

c)   Systolic BP:

 

Neonates until preschool age min is 70 mmHg.

School age and adolescents min is 80 – 90 mmHg.

Adults 90mmHg

For children 1 – 10 years old the lower limit of the systolic BP is 70+ 2 x age (in years).

 

d)  Urine Output

Infants 2 ml/kg/hour.

Children 1ml/kg/h.

Adults 0.5 ml/kg/h.

 

  e) Weight on children

For children 1 – 10 years old:

W (Kg)= (age (years) + 4 ) x 2.

 

 

Appendix (IV): Paediatric orotracheal intubation

 

The tube size is

for pre-term neonates 2.5 – 3 mm ID (internal diameter) or gestational weeks/10. 

For term neonates it is 3 – 3.5 mmID.

For infants < 1 year old it is 4 – 4.5 mmID.

For children > 1 year old use the formula: (age (years)/4 ) +4 e.g. for 8 years old kid use a size 8/4 + 4 = 6mmID.

 

Use uncuffed tubes on children < 8 years old (up to 5.5 mmID). To estimate the length of the tube, use the formulas: oral tube length (cm) = (age (years)/2) + 12. Nasal tube length (cm) = age (years)/2 + 15.

On RSI use atropine (to prevent bradycardia).

About the laryngoscope, use a straight blade (No 0 or 1) for infants (< 1year old) and neonates. On children and adolescents use curved blades (No 0, 1, 2 for infants and children; No 3 or 4 for adolescent& adults).

Don’t forget Sellick maneuver (cricoid pressure). Nasotracheal intubation is not applicable for children < 3 years old.

Neonatal orotracheal intubation. The insertion depth at the upper lip (cm) = Weight (Kg) + 6 cm.

Use a straight blade (size0 for premature and size 1 for term newborn).

About the tracheal tube size use the below guidance. GA is gestational age.

 

Tracheal tube size 2.5 mmID, Weight <1000gr, GA <28 weeks,  Insertion depth 6.5 – 7cm

Size 3 mmID, Weight 1000 – 2000 gr,  GA28 – 34 weeks,  Insertion depth 7 – 8 cm

Size 3 – 3.5 mmID, Weight  2000 – 3000 gr, GA 34 – 38 weeks, Insertion depth  8 – 9 cm

Size 3.5 – 4 mmID, Weight  >3000 gr, GA >38 weeks, Insertion depth >9 cm

 

Tracheal tube size (mmID)= gestational age (weeks)/10.

Insert the tube about 1.5 – 2 cm into the larynx, so that the black mark on the tip of the tube is just visible thru the cords.

·        DOPES (Displacement of the tube – accidental extubation or tube in the right main bronchus, Obstruction of the tube, Pneumothorax, Equipment failure, Stomach distension) should be checked if respiratory distress occurs on an intubated patient.

The first thing is to extubate the patient and ventilate him/her for a while with BMV (Bag Mask Ventilation) until you figure out the reason of the respiratory compromise. About the Equipment failure check Oxygen, bag mask, ventilator etc. Stomach distension happens frequently on children, pregnant and patients (e.g. neonates) with diaphragmatic hernia.

 

 

APPENDIX: SIGNS OF HYPOVOLAEMIC SHOCK


Signs of hypovolaemic shock (haemorrhage - external or internal blood loss; or severe dehydration e.g. on severe diarrhea or vomiting) include: tachycardia (if not on β' blockers or pacemaker!), fast thready pulse, narrowed pulse pressure (Systolic BP - diastolic BP), weak peripheral pulses, tachypnea, decreased level of concioussness (LOC), decreased urine output (adults < 0.5 ml/kg/h, children 1ml/kg/h, infants 2 ml/kg/h), decreased capillary refill time (>2 sec), hypotension (late, with > 30% volume loss on adults and > 40% on children), cool pale skin, diaphoresis (not on dehydration); also decreased skin turgor (unreliable on the elderly) and dry mucus membranes (e.g. dry tongue) on dehydration.


NOTE

Some information in this text is empirical and its reliability can't be ascertained. It is suggested to search official medical articles, books and guidelines in order to ascertain the medical information of this text.

All the medical procedures and drug administration mentioned in this text should be done only under a senior doctor's consultancy.

 

BIBLIOGRAPHY FOR EMERGENCY & ACUTE MEDICINE


1) Stone C.K., Humphries R.L., Current Diagnosis and Treatment in Emergency Medicine, McGraw Hill - LANGE, 6th edition, 2008.


2) Wyatt J.P., Illingworth R.N., Graham C.A., Clancy M.J., Robertson C.E., Oxford Handbook of Emergency Medicine, Oxford Medical Publications, 3rd edition, 2006.


3) Ramrakha P., Moore K., Oxford Handbook of Acute Medicine, Oxford Medical Publications, 2nd edition, published 2004, reprinted 2005.


4) ALS (Advanced Life Support), European Resuscitation Council, 5th edition, The Image Factory, Belgium,2006.


5) EPLS (European Paediatric Life Support), European Resuscitation Council, 3rd edition, The Image Factory, Belgium, 2006.


6) Llewelyn H., Aun Ang H., Lewis K., Al – Abdulla A., Oxford Handbook of Clinical Diagnosis, Oxford Medical Publications, 2006.

 

7) Thomas J., Monaghan T., Oxford Handbook of Clinical Examination and Practical Skills, Oxford Medical Publications, 2008.


8) Richards D., Aronson J., Oxford Handbook of Practical Drug Therapy, Oxford Medical Publications, 2008.


9) ATLS (Advanced Trauma Life Support), American College of Surgeons – Committee on Trauma, Students Course Manual, First Impression, 7th edition, 2002.


10) PHTLS (Prehospital Trauma Life Support, basic & advanced), Prehospital Trauma Life Support Committee of the National Association of Emergency Medical Technicians in association with The Committee of Trauma of the American College of Surgeons, 5th edition (revised), Mosby, inc, 2003.


11) ALSO (Advanced Life Support in Obstetrics), American Academy of Family

Physicians, 4th edition (revised), 2006.


12) Kasper D.L., Braunwald E., Fauci A.S., Hauser S.L., Longo D.L., Jameson J.L., Harrison’s Manual of Medicine, McGraw – Hill, 16th edition, 2005.


13) Simon C., Everitt H., Kendrick T., Oxford Handbook of General Practice, Oxford Medical Publications, 2nd edition, 2005.


14) Longmore M., Wilkinson I., Turmezei T., Kay Cheung C., Oxford Handbook of Clinical Medicine, Oxford Medical Publications, 7th edition, 2008.


15) Collier J., Longmore M., Brinsden M., Oxford Handbook of Clinical Specialties, Oxford Medical Publications, 7th edition, 2006.

 

16) ACLS (Advanced Cardiac Life Support), American College of Emergency Physicians, Study Guide, 2nd edition, Jones and Bartlett Publishers, 2007.

 

 

 

 

 

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